Iron absorption in normal subjects and patients with idiopathic haemochromatosis: relationship with serum ferritin concentration.

G O Walters, A Jacobs, M Worwood, D Trevett, W Thomson

In 52 normal subjects there was an inverse relationship between serum ferritin concentration and iron absorption. In 21 measurements in 15 patients with idiopathic haemochromatosis there was a similar inverse relationship but absorption was higher in relation to iron stores at all levels. Haemochromatotic patients with normal serum ferritin levels had abnormally high values for desferrioxamine chelatable iron and there was no correlation between chelatable iron and iron absorption.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

• Stuart, K A, Anderson, G J, Frazer, D M, Powell, L W, McCullen, M, Fletcher, L M, Crawford, D H G (2003). Duodenal expression of iron transport molecules in untreated haemochromatosis subjects. Gut 52: 953-959 [Abstract] [Full Text]  
• Roughead, Z. K, Zito, C. A, Hunt, J. R (2002). Initial uptake and absorption of nonheme iron and absorption of heme iron in humans are unaffected by the addition of calcium as cheese to a meal with high iron bioavailability. Am. J. Clin. Nutr. 76: 419-425 [Abstract] [Full Text]  
• Fomon, S. J., Ziegler, E. E., Serfass, R. E., Nelson, S. E., Rogers, R. R., Frantz, J. A. (2000). Less Than 80% of Absorbed Iron Is Promptly Incorporated into Erythrocytes of Infants. J. Nutr. 130: 45-52 [Abstract] [Full Text]  
• Moura, E., Noordermeer, M. A., Verhoeven, N., Verheul, A. F.M., Marx, J. J.M. (1998). Iron Release From Human Monocytes After Erythrophagocytosis In Vitro: An Investigation in Normal Subjects and Hereditary Hemochromatosis Patients. Blood 92: 2511-2519 [Abstract] [Full Text]  
• Santos, M., Clevers, H., de Sousa, M., Marx, J.J.M. (1998). Adaptive Response of Iron Absorption to Anemia, Increased Erythropoiesis, Iron Deficiency, and Iron Loading in beta 2-Microglobulin Knockout Mice. Blood 91: 3059-3065 [Abstract] [Full Text]  
• Halliday, J. W., Mack, U., Powell, L. W. (1978). Duodenal Ferritin Content and Structure: Relationship With Body Iron Stores in Man. Arch Intern Med 138: 1109-1113 [Abstract]