Are complications of endoscopic sphincterotomy age related?
G T Deans
a Stockport Unit for
Minimally Invasive Therapy, Stepping Hill Hospital, Stockport SK2 7JE,
UK, b Hull Royal Infirmary,
Hull, UK, c South
Manchester University Hospital, Manchester, UK, d Royal Hallamshire Hospital, Sheffield, UK
Correspondence to: Mr Deans. Accepted for publication 2 June 1997 Background Keywords:
Endoscopic retrograde cholangiopancreatography;
laparoscopic cholecystectomy;
aging
Endoscopic retrograde
cholangiopancreatography sphincterotomy is increasingly performed
in younger patients undergoing laparoscopic cholecystectomy.
However, the safety of endo- scopic sphincterotomy in this age group,
relative to that in older patients, is unknown.
Aim
To determine whether the development of short
term complications following endoscopic sphincterotomy is age related.
Patients and methods
A prospective multicentre
audit of 958 patients (mean age 73, range 14-97, years) undergoing a
total of 1000 endoscopic sphincterotomies.
Results
Two deaths occurred, both from
postsphincterotomy acute pancreatitis. Postprocedural complications
developed in 24 patients: pancreatitis in 10, ascending cholangitis in
seven, bleeding in four, and retroperitoneal perforation in three.
There were six complications (five cases of pancreatitis and one bleed; 2.2%) and no deaths in the 281 (29.3%) patients aged under 65 years.
In comparison, 18 (2.6%) of the 677 patients aged over 65 years
developed a complication (cholangitis in seven, pancreatitis in five,
bleeding in three, and perforation in three). Patients under 35, 45, 55, and 65 years were not at significantly increased risk of
complication than those over these ages (relative risk for those under
compared with those over 65 years 0.83, 95% confidence intervals
0.41-1.67, p=0.74).
Conclusion
Short term complications following
endoscopic sphincterotomy are not related to age. Younger patients
undergoing laparoscopic cholecystectomy need not be denied endoscopic
sphincterotomy for fear that the risks are greater than if they undergo
surgical exploration of the common bile duct.
(GUT 1997;41:545-548)
© 1997 by Gut
Relevant Article
- Aging and the alimentary tract
- MICHAEL FARTHING and OLIVER JAMES
Gut 1997 41: 421.[Extract] [Full Text] [PDF]
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