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Gut 2004;53:917-918; doi:10.1136/gut.2003.026971
Copyright © 2004 BMJ Publishing Group Ltd & British Society of Gastroenterology.

LEADING ARTICLE

Expression profiling: fishing and chips

I P Hall

Correspondence to:
Correspondence to:
Professor I P Hall
Division of Therapeutics and Molecular Medicine, D Floor, South Block, Queen’s Medical Centre, Nottingham NG7 2UH, UK; ian.hall{at}nottingham.ac.uk

Expression profiling approaches are potentially valuable in helping to define novel gene products which may be important in disease pathogenesis or treatment response. However, there are many pitfalls which need to be considered in the design of experiments of this kind and in considering interpretation of data from such studies. Some of these are discussed.

Keywords: micorarray; cell signalling; chip; expression profiling; gene expression


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