LEADING ARTICLE
Ecological control of the gastrointestinal tract. The role of probiotic flora
| The first 150 words of the full text of this article appear below. |
| |
The "new" lifestyle a threat to health? |
|---|
It is increasingly evident that human diseases are most often
related to lifestyle, and should in theory be preventable. The stress
of modern life, our reduced physical activity, and our consumption
of manipulated and processed foods, and of chemicals
including pharmaceuticals
all contribute to our decreasing resistance to disease. Much evidence supports the fact that our genes, adapted during
millions of years to the lifestyle of our prehistoric ancestors, tolerate poorly the dramatic changes in lifestyle that have occurred, especially in food habits during the past 100 years.1
Changes in food habits in Western countries that no doubt constitute
stresses to the human body and that may predispose to inflammatory,
infectious, ulcerative, degenerative, and neoplastic diseases include
the following: the consumption of 100 lb refined sugar per individual per year; the 10-fold increase in sodium consumption; the fourfold increase in consumption of saturated fat; the doubled consumption of
cholesterol; a much reduced
This article has been cited by other articles:
-
Sheth, A., Floch, M.
(2009). Probiotics and Diverticular Disease. Nutr Clin Pract
24: 41-44
[Abstract] [Full Text] -
Stefan, N., Kantartzis, K., Haring, H.-U.
(2008). Causes and Metabolic Consequences of Fatty Liver. Endocr. Rev.
29: 939-960
[Abstract] [Full Text] -
Zoetendal, E G, Rajilic-Stojanovic, M, de Vos, W M
(2008). High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota. Gut
57: 1605-1615
[Abstract] [Full Text] -
Vicente, J., Higgins, S., Bielke, L., Tellez, G., Donoghue, D., Donoghue, A., Hargis, B.
(2007). Effect of Probiotic Culture Candidates on Salmonella Prevalence in Commercial Turkey Houses. J. Appl. Poult. Res.
16: 471-476
[Abstract] [Full Text] -
Gamage, S. D., Patton, A. K., Strasser, J. E., Chalk, C. L., Weiss, A. A.
(2006). Commensal Bacteria Influence Escherichia coli O157:H7 Persistence and Shiga Toxin Production in the Mouse Intestine. Infect. Immun.
74: 1977-1983
[Abstract] [Full Text] -
Coolen, M. J. L., Post, E., Davis, C. C., Forney, L. J.
(2005). Characterization of Microbial Communities Found in the Human Vagina by Analysis of Terminal Restriction Fragment Length Polymorphisms of 16S rRNA Genes. Appl. Environ. Microbiol.
71: 8729-8737
[Abstract] [Full Text] -
Ventura, M., Canchaya, C., Zink, R., Fitzgerald, G. F., van Sinderen, D.
(2004). Characterization of the groEL and groES Loci in Bifidobacterium breve UCC 2003: Genetic, Transcriptional, and Phylogenetic Analyses. Appl. Environ. Microbiol.
70: 6197-6209
[Abstract] [Full Text] -
Ventura, M., Canchaya, C., van Sinderen, D., Fitzgerald, G. F., Zink, R.
(2004). Bifidobacterium lactis DSM 10140: Identification of the atp (atpBEFHAGDC) Operon and Analysis of Its Genetic Structure, Characteristics, and Phylogeny. Appl. Environ. Microbiol.
70: 3110-3121
[Abstract] [Full Text] -
Sheil, B, McCarthy, J, O'Mahony, L, Bennett, M W, Ryan, P, Fitzgibbon, J J, Kiely, B, Collins, J K, Shanahan, F
(2004). Is the mucosal route of administration essential for probiotic function? Subcutaneous administration is associated with attenuation of murine colitis and arthritis. Gut
53: 694-700
[Abstract] [Full Text] -
Yamaguchi, H., Osaki, T., Taguchi, H., Sato, N., Toyoda, A., Takahashi, M., Kai, M., Nakata, N., Komatsu, A., Atomi, Y., Kamiya, S.
(2003). Effect of Bacterial Flora on Postimmunization Gastritis following Oral Vaccination of Mice with Helicobacter pylori Heat Shock Protein 60. CVI
10: 808-812
[Abstract] [Full Text] -
McCarthy, J, O'Mahony, L, O'Callaghan, L, Sheil, B, Vaughan, E E, Fitzsimons, N, Fitzgibbon, J, O'Sullivan, G C, Kiely, B, Collins, J K, Shanahan, F
(2003). Double blind, placebo controlled trial of two probiotic strains in interleukin 10 knockout mice and mechanistic link with cytokine balance. Gut
52: 975-980
[Abstract] [Full Text] -
Ibnou-Zekri, N., Blum, S., Schiffrin, E. J., von der Weid, T.
(2003). Divergent Patterns of Colonization and Immune Response Elicited from Two Intestinal Lactobacillus Strains That Display Similar Properties In Vitro. Infect. Immun.
71: 428-436
[Abstract] [Full Text] -
McNaught, C E, Woodcock, N P, MacFie, J, Mitchell, C J
(2002). A prospective randomised study of the probiotic Lactobacillus plantarum 299V on indices of gut barrier function in elective surgical patients. Gut
51: 827-831
[Abstract] [Full Text] -
Duggan, C., Gannon, J., Walker, W A.
(2002). Protective nutrients and functional foods for the gastrointestinal tract. Am. J. Clin. Nutr.
75: 789-808
[Abstract] [Full Text] -
Buddington, K. K., Donahoo, J. B., Buddington, R. K.
(2002). Dietary Oligofructose and Inulin Protect Mice from Enteric and Systemic Pathogens and Tumor Inducers. J. Nutr.
132: 472-477
[Abstract] [Full Text] -
Pinchuk, I. V., Bressollier, P., Verneuil, B., Fenet, B., Sorokulova, I. B., Megraud, F., Urdaci, M. C.
(2001). In Vitro Anti-Helicobacter pylori Activity of the Probiotic Strain Bacillus subtilis 3 Is Due to Secretion of Antibiotics. Antimicrob. Agents Chemother.
45: 3156-3161
[Abstract] [Full Text] -
de Waard, R., Garssen, J., Snel, J., Bokken, G. C. A. M., Sako, T., Huis in 't Veld, J. H. J., Vos, J. G.
(2001). Enhanced Antigen-Specific Delayed-Type Hypersensitivity and Immunoglobulin G2b Responses after Oral Administration of Viable Lactobacillus casei YIT9029 in Wistar and Brown Norway Rats. CVI
8: 762-767
[Abstract] [Full Text] -
Walker, W A.
(2001). Introduction. Am. J. Clin. Nutr.
73: 1121S-1123
[Full Text] -
Isolauri, E.
(2001). Probiotics in human disease. Am. J. Clin. Nutr.
73
: 1142S-1146S
[Abstract] [Full Text] -
Dunne, C., O'Mahony, L., Murphy, L., Thornton, G., Morrissey, D., O'Halloran, S., Feeney, M., Flynn, S., Fitzgerald, G., Daly, C., Kiely, B., O'Sullivan, G. C, Shanahan, F., Collins, J K.
(2001). In vitro selection criteria for probiotic bacteria of human origin: correlation with in vivo findings. Am. J. Clin. Nutr.
73: 386S-392
[Abstract] [Full Text] -
Stanton, C., Gardiner, G., Meehan, H., Collins, K., Fitzgerald, G., Lynch, P B., Ross, R P.
(2001). Market potential for probiotics. Am. J. Clin. Nutr.
73: 476S-483
[Abstract] [Full Text] -
Grönlund, M-M, Arvilommi, H, Kero, P, Lehtonen, O-P, Isolauri, E
(2000). Importance of intestinal colonisation in the maturation of humoral immunity in early infancy: a prospective follow up study of healthy infants aged 0-6 months. Arch. Dis. Child. Fetal Neonatal Ed.
83: 186F-192
[Abstract] [Full Text] -
Metges, C. C.
(2000). Contribution of Microbial Amino Acids to Amino Acid Homeostasis of the Host. J. Nutr.
130: 1857S-1864
[Abstract] [Full Text] -
Metges, C. C, Petzke, K. J, El-Khoury, A. E, Henneman, L., Grant, I., Bedri, S., Regan, M. M, Fuller, M. F, Young, V. R
(1999). Incorporation of urea and ammonia nitrogen into ileal and fecal microbial proteins and plasma free amino acids in normal men and ileostomates. Am. J. Clin. Nutr.
70: 1046-1058
[Abstract] [Full Text] -
Metges, C. C., El-Khoury, A. E., Henneman, L., Petzke, K. J., Grant, I., Bedri, S., Pereira, P. P., Ajami, A. M., Fuller, M. F., Young, V. R.
(1999). Availability of intestinal microbial lysine for whole body lysine homeostasis in human subjects. Am. J. Physiol. Endocrinol. Metab.
277: E597-E607
[Abstract] [Full Text]
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
a threat to health?