LEADING ARTICLE
Inflammatory bowel disease incidence: up, down or unchanged?
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Introduction |
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One of the few aspects of the epidemiology of inflammatory
bowel disease (IBD) that seems indisputable is the emergence of both
ulcerative colitis and Crohn's disease in the economically developed
nations of Western Europe and North America during the past
century.1 Some of the apparent increase in incidence
undoubtedly reflects a receding tide of mimicking infectious diseases
and developments in endoscopic and other diagnostic techniques.
Nevertheless, most epidemiologists accept that there were considerable
real increases in ulcerative colitis incidence during the first half of
this century and of Crohn's disease incidence during the middle half-century in these countries.2 As the millennium
approaches, are the incidences of each disease continuing to increase?
Some reports suggest they are, whereas claims that Crohn's disease incidence is no longer increasing can provoke a rapid response from
some clinicians.3-6 At a time when basic science is
making progress by leaps and bounds, why should such
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