COMMENTARY
See article on page 330
Gastro-oesophageal reflux: does it matter what you eat?
| The first 150 words of the full text of this article appear below. |
Patients with gastro-oesophageal reflux (GORD) are usually advised to modify their dietary habits.1 Among the most popular beliefs is the recommendation to avoid fatty foods which are thought to be detrimental in GORD for several reasons, including reduced lower oesophageal sphincter tone2 and delayed gastric emptying. This latter effect may, in turn, result in an increase in the number of transient lower oesophageal sphincter relaxations (TLOSRs) elicited through a vago-vagal reflex originating in the mechanoreceptors located in the subcardial area.3 TLOSRs are considered to be the main motor mechanism associated with the occurrence of reflux episodes both in asymptomatic subjects and reflux patients with or without oesophagitis.
With regard to the therapeutic benefit of a low fat regimen in GORD, a
review of the literature has shown that there is a paucity of data to
support the effectiveness of such a recommendation and no controlled
trials.1 However, early studies attempted
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- Effect of increasing the fat content but not the energy load of a meal on gastro-oesophageal reflux and lower oesophageal sphincter motor function
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