Management of Helicobacter pylori infection in children
G Oderda
Dipartimento di Scienze
Mediche, Università di Torino
Correspondence to: Dr G Oderda, Clinica Pediatrica, Dipartimento di Scienze Mediche, Università di Torino, Via Solaroli 17, 28100 Novara, Italy.
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Summary |
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When trying to decide which children with Helicobacter
pylori infection should be treated and at what stage they should
be tested, we should take into account the fact that eradication of the
infection may be useful both to induce symptom remission and to prevent
later complications in adulthood. However, well designed studies to
identify those infected children who are at risk of developing
complications or have symptoms due to the infection are still lacking.
Current literature only gives information on how to treat children with
H pylori infection. Treatment regimens that include two
drugs are usually more effective than in adults, and produce an
eradication rate of 70-80%, but they should be given for at least two
weeks, shorter treatments being less effective. Antibiotic resistance
can impair eradication rate and the frequency of resistant strains in
children should be studied. Combinations of antibiotics with
antisecretory drugs are highly effective in
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Street, M E, Caruana, P, Caffarelli, C, Magliani, W, Manfredi, M, Fornaroli, F, de'Angelis, G L
(2001). Antibiotic resistance and antibiotic sensitivity based treatment in Helicobacter pylori infection: advantages and outcome. Arch. Dis. Child.
84: 419-422
[Abstract] [Full Text]
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