Commentary
See article on page 798Giving carditis back to the heart
| The first 150 words of the full text of this article appear below. |
Anatomically vague (it was named after its proximity to the heart), histologically undistinguished (its mucosa is usually described as being "similar to the mucosa of the antrum") and functionally considered a drab territory that connects two well characterised segments of the digestive system, the gastric cardia has long been ignored by gastroenterologists, pathologists, and physiologists alike.
Suddenly, in the past few years, this neglected Grenz zone has been catapulted to the centre of the gastroenterological stage. Another spin-off of Helicobacter pylori? In a sense, yes. But, whereas the wily bacterium is blamed for a long list of calamities occurring in the remainder of the stomach, duodenum, and other systems, in the cardia it is portrayed as a protector of mucosal integrity.1 An implausible defensor mucosae.
During the past few decades a dramatic rise in the incidence of
adenocarcinoma of the cardia has been reported in the very populations
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