Commentary
See article on page 533Colorectal cancer survival in Europe: the Will Rogers phenomenon revisited
| The first 150 words of the full text of this article appear below. |
Colorectal cancer (CRC) is one of the leading causes of cancer death in Europe. In this issue of Gut, Gatta and colleagues1 report survival results from a population based study involving 2270 cases of CRC from 11 cancer registries in six European countries (see page 533). The authors report a surprisingly wide range of overall survival among the registries; three year survival varied from a low of 25% in Cracow, Poland to a high of 59% in Modena, Italy. An understanding of the causes for this wide variation could serve as the database for efforts to improve the overall outcome of CRC.
It is well established that the prognosis of CRC is dependent on
factors related to the tumour, the patient, and the treatment of the
disease. More advanced stage, location of the cancer in the rectum,
poorly differentiated histology, vascular invasion, and older age are
all associated with a
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- G Gatta, R Capocaccia, M Sant, C M J Bell, J W W Coebergh, R A M Damhuis, J Faivre, C Martinez-Garcia, J Pawlega, M Ponz de Leon, D Pottier, N Raverdy, E M I Williams, and F Berrino
Gut 2000 47: 533-538.[Abstract] [Full Text] [PDF]
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