Commentary
See article on page 522The changing scope of colorectal cancer
| The first 150 words of the full text of this article appear below. |
The prognosis in colorectal cancer depends on the stage at
which the disease is diagnosed. Patients with advanced disease usually
die of cancer, but when large intestinal tumours are found at an early
asymptomatic phase a cure can be anticipated. Furthermore, the
premalignant lesions
adenomatous polypsgrow in the colon for
years and perhaps decades before malignant conversion occurs, providing
an opportunity for their removal, interrupting the natural history of
these neoplasms. It has long been recognised that preventive strategies
would be appropriate for this disease, and an extensive literature can
be found on the subject
Two general approaches to detecting asymptomatic early staged
colorectal cancers have been studied in dept. The first is the use of
faecal occult blood tests as colorectal neoplasms add blood to the
stool that can be detected prior to the development of symptoms.
However, this approach is relatively weak due to deficiencies in both
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