Debate
Antagonist: Should we eradicate Helicobacter pylori in non-ulcer dyspepsia?
D Pantoflickova, A L BlumDivision of
Gastroenterology, Department of Medicine, University Hospital, CHUV,
CH-1011 Lausanne, Switzerland
Correspondence to: AL Blum, Rue de Collège, CH1323 Romainmotier, Switzerland. andre.blum@chuv.hospvd.ch
Accepted for publication 31 October 2000
| The first 150 words of the full text of this article appear below. |
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Introduction |
|---|
Treatment of Helicobacter pylori
infection in non-ulcer dyspepsia (NUD) should only be recommended if
the following
still unprovedassociations can be made. Firstly,
epidemiological studies show a link between H
pylori and dyspeptic symptoms and, secondly, treatment studies
demonstrate such a link (table 1). We will examine results from these
two types of studies.
| Table Removed (Available Only in the Full Text) |
| |
Epidemiological studies |
|---|
Forty two epidemiological studies compared the prevalence of H pylori infection in dyspeptic patients and asymptomatic controls (see website fig 1). Meaningful studies should use the following design: an appropriate definition of dyspepsia; adequate sample size; dyspeptic subjects and controls sampled from the general population; and results adjusted for potential confounders such as age, sex, smoking, ethnicity, and socioeconomic status.
Of 20 endoscopic studies, only two were population based and used
adequate controls matched at least for age and sex (see website fig
1A).1 2 The prevalence of H
pylori infection in NUD subjects and in asymptomatic
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This article has been cited by other articles:
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