Leading article
Non-pylori helicobacter species in humans
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Introduction |
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The discovery of Helicobacter pylori in 1982 increased interest in the range of other spiral bacteria that had been seen not only in the stomach but also in the lower bowel of many animal species.1 2 The power of technologies such as the polymerase chain reaction with genus specific primers revealed that many of these bacteria belong to the genus Helicobacter. These non-pylori helicobacters are increasingly being found in human clinical specimens. The purpose of this article is to introduce these microorganisms to the clinician, put them in an ecological perspective, and to reflect on their likely importance as human pathogens.
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Gastric bacteria |
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In 1987, Dent et al described the
presence of a novel bacterium in 3/1300 gastric biopsies.3
The initial differentiation was based on morphology, the bacterium
having a larger tight helical shape compared to the S shape of
H pylori (fig 1). Subsequent studies have
shown that while rarely found in
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