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Gut 2001;49:614-616; doi:10.1136/gut.49.5.614
Copyright © 2001 BMJ Publishing Group Ltd & British Society of Gastroenterology.
Gut 2001;49:614-616 ( November )

Debate

Protagonist: Should we eradicate Helicobacter pylori before long term antireflux therapy?

J Labenz

Jung-Stilling Hospital, Wichernstr. 40, D-57074 Siegen, Germany

Correspondence to: Dr J Labenz, J.Labenz@t-online.de

Accepted for publication 5 June 2001

The first 150 words of the full text of this article appear below.

    Introduction

Helicobacter pylori infection invariably induces chronic active gastritis which can give rise to serious consequences such as peptic ulcer and gastric malignancies. Generally accepted indications for treatment are H pylori associated peptic ulcer disease and early stages of low grade mucosa associated lymphoid tissue lymphoma of the stomach. In contrast, treatment of H pylori in patients with gastro-oesophageal reflux disease (GORD) requiring long term treatment with a proton pump inhibitor (PPI) has not yet been put on a scientific footing. In support of this indication in patients with GORD and no associated ulcer disease, the following theoretical arguments might be advanced.

In contrast, treatment of H pylori in patients with gastro-oesophageal reflux desease (GORD) requiring long term treatment with a proton pump inhibitor (PPI) has not yet been put on a scientific footing. In support of this indication in patients with GORD and no associated ulcer disease, the following theoretical . . . [Full text of this article]


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This article has been cited by other articles:

  • Malfertheiner, P (2004). Helicobacter pylori eradication does not exacerbate gastro-oesophageal reflux disease. Gut 53: 312-313 [Abstract] [Full Text]  

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