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Gut 2001;49(Suppl I):I1-I21 ( July )

Clinical guidelines on the management of hepatitis C

J C L Bootha, J O'Gradyb, J Neubergerc, on behalf of the Royal College of Physicians of London and the British Society of Gastroenterology

a Department of Gastroenterology, Royal Berkshire Hospital, London Road, Reading RG5 5AN, UK, b Institute of Liver Studies, King's College London, Bessemer Road, London SE5 9PJ, UK, c The Liver and Hepatobiliary Unit, Queen Elizabeth Hospital, Birmingham B15 2TH, UK

Correspondence to: Dr J C L Booth.

The first 150 words of the full text of this article appear below.

    1.0 Guidelines

1.1 THE NEED FOR GUIDELINES
Hepatitis C virus (HCV) is a major health care concern in the UK affecting some 200 000 to 400 000 individuals. The majority of these patients will have chronic HCV infection and many will develop chronic liver disease with the risk of developing cirrhosis and hepatocellular carcinoma (HCC). Successful treatment will arrest the progression of liver disease and so prevent the serious complications of chronic HCV infection. In addition, treatment will reduce the numbers of HCV infected individuals.

The relatively high cost of treatment enforces the need for a systematic approach for this condition so that resources are used most effectively. The development of clinical guidelines is important, as these will assist purchasing authorities, providers, clinicians, primary care groups, and patients in making decisions about appropriate treatment.

1.2 THE DEVELOPMENT OF GUIDELINES: RIGOUR OF DEVELOPMENT/SYSTEMATIC CRITICAL REVIEW OF THE LITERATURE

1.2.1 Guideline development group
The development of . . . [Full text of this article]




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