© 2002 by Gut
DISCUSSION IV
Discussion IV
Keywords: omeprazole; proton pump inhibitor; Helicobacter pylori; gastro-oesophageal reflux disease
Dr Fennerty: None of the studies looked at patients in the long term. I would find the lowest effective dose that leaves patients in remission, and then continue treating with this dose.
Professor Talley: As a gastroenterologist, when such a patient comes to me of course I will investigate him/her further, because that is why patients are sent to me. We really need to ask a primary care physician whether, in a young patient who does not have alarm features, who is H pylori negative, and in whom acid suppressive therapy has failed, further tests would be performed or whether other treatments would be tried. Based on my discussions, it seems that most primary care physicians would feel reassured that the patient does not have a serious disease.
Professor Dent: The role of gastric emptying as a major factor in causing GORD has, in my opinion, been overrated. Many patients
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