© 2002 by Gut
COMMENTARY
Irritable bowel syndrome and the enteric nervous system
Infection and irritability
Academic Department of Medicine, University Hospital of South Manchester, Manchester, UK
Correspondence to:
Correspondence to:
Dr P J Whorwell, Academic Department of Medicine, Education and Research Centre, Wythenshawe Hospital, Southmoor Road, Wythenshawe, Manchester M23 9LT, UK;
peter.whorwell@smuht.nwest.nhs.uk
A proportion of patients with irritable bowel syndrome report an apparent association between the onset of symptoms and a dysenteric illness
Keywords: irritable bowel syndrome; infection; mental health; prognosis
| The first 150 words of the full text of this article appear below. |
Chaudhary and Truelove were amongst the first to recognise that a proportion of patients with irritable bowel syndrome (IBS) report an apparent association between the onset of symptoms and a dysenteric illness.1 The concept of "post-dysenteric IBS" (PD-IBS) has now been widely accepted with claims suggesting that it accounts for anything up to 25% of the totality of the condition. However, careful questioning of these patients sometimes, but not always, suggests that they may have had a "forme fruste" of the disorder before their infection, raising the possibility that there may be two forms of the illness, one being an exacerbation of a pre-existing disorder and another where the condition appears to arise de novo. Ultimately, issues surrounding the natural history of PD-IBS will only be resolved by detailed prospective and retrospective studies, such as the one reported by Neal and colleagues2
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Gut 2002 51: 410-413.[Abstract] [Full Text] [PDF]
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