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Gut 2003;52:462-463; doi:10.1136/gut.52.4.462
Copyright © 2003 BMJ Publishing Group Ltd & British Society of Gastroenterology.
Gut 2003;52:462-463
© 2003 by BMJ Publishing Group & British Society of Gastroenterology

CLINICAL @LERT

Transplantation for alcoholic liver disease: lessons from the explant?

A Bathgate, P Hayes

Scottish Liver Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, UK

Correspondence to:
Correspondence to:
Professor P Hayes;
p.hayes@ed.ac.uk


Outcome of liver transplantation for patients with end stage alcoholic cirrhosis is not different from those with superimposed alcoholic hepatitis

Keywords: alcoholic hepatitis; liver transplantation; alcoholic liver disease; liver disease

The first 150 words of the full text of this article appear below.

Orthotopic liver transplantation for alcoholic cirrhosis is now well established, with good outcome in terms of patient and graft survival. Transplantation for alcoholic hepatitis however is not a recognised indication in the UK.1 All centres in the UK require a period of abstinence before listing for transplantation, although not all have input from psychiatrists experienced in alcohol dependence.2


Tomé S, Martinez-Rey C, Gonzalez-Quintela A, et al. Influence of superimposed alcoholic hepatitis on the outcome of liver transplantation for end-stage alcoholic liver disease. J Hepatol 2002;36:793–8.[CrossRef][Medline]

Background: End stage alcoholic liver disease (ALD) is a common indication for liver transplantation but alcoholic hepatitis (AH) is often regarded as a contraindication. There is little evidence to support this belief.

Objective: To study the effect of superimposed AH on the outcome of liver transplantation for end stage ALD.

Design: Case series of consecutive patients undergoing liver . . . [Full text of this article]



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