© 2003 by BMJ Publishing Group & British Society of Gastroenterology
Digest
| The first 150 words of the full text of this article appear below. |
The afferent neurones of the gastric mucosa are known to respond to noxious chemicals such as ethanol in a protective way and form the "neural emergency system". The release of the vasodilatory peptide calcitonin gene related peptide (CGRP) from these nerves ameliorates the impairment of mucosal blood flow that alcohol and other noxious agents induce. The paper by Arai et al in this issue using a range of pharmacological manipulations in wild type and prostaglandin I2 (prostacyclin) receptor knock-out animals now add to our knowledge by showing that endogenous prostaglandin enhance this neural emergency system. Furthermore it seems that prostaglandin I2 is the most important of the prostaglandins since prostaglandin I receptor knock-out mice do not demonstrate the protective action of capsaicin.See page 1242
The control of T cell proliferation and activity in Helicobacter pylori induced gastritis is poorly characterised. The paper by Futagami et al demonstrates in vitro
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Relevant Articles
- Endogenous prostaglandin I2 regulates the neural emergency system through release of calcitonin gene related peptide
- K Arai, T Ohno, T Saeki, S Mizuguchi, K Kamata, I Hayashi, K Saigenji, T Murata, S Narumiya, and M Majima
Gut 2003 52: 1242-1249.[Abstract] [Full Text] [PDF]
- Monocyte chemoattractant protein 1 (MCP-1) released from Helicobacter pylori stimulated gastric epithelial cells induces cyclooxygenase 2 expression and activation in T cells
- S Futagami, T Hiratsuka, A Tatsuguchi, K Suzuki, M Kusunoki, Y Shinji, K Shinoki, T Iizumi, T Akamatsu, H Nishigaki, K Wada, K Miyake, K Gudis, T Tsukui, and C Sakamoto
Gut 2003 52: 1257-1264.[Abstract] [Full Text] [PDF]
- Immunomodulatory effects of inhaled carbon monoxide on rat syngeneic small bowel graft motility
- A Nakao, B A Moore, N Murase, F Liu, B S Zuckerbraun, F H Bach, A M K Choi, M A Nalesnik, L E Otterbein, and A J Bauer
Gut 2003 52: 1278-1285.[Abstract] [Full Text] [PDF]
- Telomere shortening of epithelial cells characterises the adenoma-carcinoma transition of human colorectal cancer
- R R Plentz, S U Wiemann, P Flemming, P N Meier, S Kubicka, H Kreipe, M P Manns, and K L Rudolph
Gut 2003 52: 1304-1307.[Abstract] [Full Text] [PDF]
- Risk of hepatitis C virus transmission from patients to surgeons: model based on an unlinked anonymous study of hepatitis C virus prevalence in hospital patients in Glasgow
- D Thorburn, K Roy, S O Cameron, J Johnston, S Hutchinson, E A B McCruden, P R Mills, and D J Goldberg
Gut 2003 52: 1333-1338.[Abstract] [Full Text] [PDF]
Services
- Email this link to a friend
- Similar articles in this journal
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
