© 2004 by BMJ Publishing Group Ltd & British Society of Gastroenterology
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| The first 150 words of the full text of this article appear below. |
Most gastroenterologists endoscope many patients with reflux each week. The findings of the large endoscopic study reported by Meining et al has important implications about the decision of whether or not to biopsy a normal looking Z line looking for Barrett’s oesophagus. This study of 929 patients from Munich found poor reproducibility, particularly in patients in whom the histological and endoscopic findings conflicted. When repeated an average of 31 months later only 37% of original findings were confirmed. The authors felt that this related to retching and sampling errors in a condition that may be patchy. They also concluded that biopsying an endoscopically normal Z line cannot be recommended at present and called for more reliable techniques to detect Barrett’s oesophagus and/or dysphasia at the oesophago-gastric junction. Magnifying endoscopy and staining might be valuable in this respect, but are as yet unproven.
See p 1402
The incidence of celiac disease
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