© 2005 by BMJ Publishing Group Ltd & British Society of Gastroenterology
COMMENTARY
Gastric cancer
Screening for early gastric cancer
Correspondence to:
Correspondence to:
Professor K E L McColl
Section of Medicine, Western Infirmary, 44 Church St, Glasgow, UK; k.e.l.mccoll@clinmed.gla.ac.uk
Can serological testing for Helicobacter pylori infection and atrophic gastritis predict the risk of gastric cancer?
Keywords: Helicobacter pylori; gastric cancer; surveillance; pepsinogens; risk assessment
| The first 150 words of the full text of this article appear below. |
Gastric cancer remains one of the most common malignancies in the world.1 The great majority of cases are fatal because the tumour has usually reached an incurable stage by the time of diagnosis.2 The early potentially curable stage of the disease is usually asymptomatic and consequently patients mainly present when they have developed symptoms of advanced or complicated disease.2,3 There is considerable interest in a means of detecting this common cancer at an early and curable stage.
In the Western world, the incidence of gastric cancer distal to the cardia has fallen over recent decades whereas that at the cardia and gastro-oesophageal junction has increased markedly.4 However, at a global level, non-cardia gastric cancer remains the predominant type and it is this which we are discussing.1
Major advances have been made in our understanding of the aetiology and pathogenesis of non-cardia gastric cancer and of the precancerous changes
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Gut 2005 54: 764-768.[Abstract] [Full Text] [PDF]
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