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Leukotriene receptor antagonists as potential steroid sparing agents in a patient with serosal eosinophilic gastroenteritis

M Kujundi

M Bani

T Vei

¹ Department of Internal Medicine, Clinical Hospital Dubrava, Zagreb, Croatia
² Department of Internal Medicine, General Hospital Sveti Duh, Zagreb, Croatia
³ Department of Cytology, Clinical Hospital Dubrava, Zagreb, Croatia
⁴ Department of Internal Medicine, Clinical Hospital Dubrava, Zagreb, Croatia

Correspondence to:
Correspondence to:
Dr M C Urek
Department of Internal Medicine, Clinical Hospital Dubrava, Domagojeva 9, 10000 Zagreb, Croatia; murek@kbd.hr

Keywords: leukotrienes; leukotriene receptor antagonists; serosal eosinophilic gastroenteritis; gastroenteritis

The first 150 words of the full text of this article appear below.

Eosinophilic gastroenteritis is a heterogeneous and uncommon disorder characterised by eosinophilic inflammation of the gastrointestinal tissues. The location and depth of infiltration determine its various manifestations and later serve as the basis for its classification as mucosal, muscular, and serosal forms of eosinophilic gastroenteritis. The gold standard for diagnosis is an endoscopic biopsy showing prominent tissue eosinophilia. Gastrointestinal mucosal involvement causes malabsorption, protein losing enteropathy, and diarrhoea. Infiltration of the muscular layer of the bowel wall may cause gastric outlet or small bowel obstruction. Serosal involvement causes exudative ascites rich in eosinophils; this is the least common form and is usually diagnosed by laparoscopic examination and biopsy of the whole intestinal wall.^1,2

We present the case of an 18 year old male student with a history of allergic rhinitis presenting with abdominal pain, nausea, and low grade fever, which started a few weeks before his admission. Medical history was unremarkable . . . [Full text of this article]