HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS REGISTER		Author Keyword(s) Vol Page [Advanced]

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this link to a friend Similar articles in this journal Similar articles in PubMed Add article to my folders Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Angelberger, S Articles by Dejaco, C Search for Related Content PubMed PubMed Citation Articles by Angelberger, S Articles by Dejaco, C

Prevention of abortion by ciclosporin treatment of fulminant ulcerative colitis during pregnancy

Medical University of Vienna, Department of Internal Medicine IV, Division of Gastroenterology and Hepatology, Vienna, Austria

Correspondence to:
Correspondence to:
Dr C Dejaco
Medical University of Vienna, Department of Internal Medicine IV, Division of Gastroenterology and Hepatology, Währinger Gürtel 18–20, 1090 Vienna, Austria; clemens.dejaco@meduniwien.ac.at

Keywords: ulcerative colitis; pregnancy; ciclosporin; treatment

The first 150 words of the full text of this article appear below.

Ciclosporin (CsA) is an established treatment in severe, intravenous corticosteroid resistant ulcerative colitis (UC). Although one third of UC patients relapse during pregnancy, experience with CsA use during this period is limited to a few case reports.¹ Most of the available data on CsA administration and pregnancy outcome have been obtained from the transplantation literature.² We read the letter of Jayaprakash and colleagues (Gut 2004;53:1386–7) who described the case of a patient with fulminant corticosteroid resistant distal UC successfully treated with CyA and delivering a healthy baby. Herein we report the dramatic case of a 21 year old primigravida with a diagnosis of UC (in April 2000) who experienced a fulminant flare at the end of her first trimester despite immunosuppressive treatment and whose pregnancy could only be preserved by intravenous CsA therapy.

At time of conception in June 2003 the patient was in stable clinical remission, . . . [Full text of this article]