EDITOR'S QUIZ: GI SNAPSHOT
EDITOR’S QUIZ: GI SNAPSHOT
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From question on page 905
The patient had multiple lymphomatous polyposis (MLP) due to the involvement of gastrointestinal tract in mantle cell lymphoma.
Endoscopic ultrasonography with a catheter probe on the gastric wall (fig 3) showed a prominently thickened subepithelial layer. Microscopic examination showed that monotonous small lymphoma cells infiltrated the lamina propria in the endoscopic gastric biopsy specimen (see answer fig 1
). Immunohistochemical staining of both tonsilar biopsy and endoscopic biopsy specimens confirmed mantle cell lymphoma. The patient has been followed up and has received three courses of chemotherapy during the 19 months since the initial episode.
Figure 1 Photomicrograph of the gastric biopsy specimen showing numerous small lymphoma cells with bizarre nuclei infiltrating the lamina propria (H&E stain, original magnification x40).
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MLP describes the unique endoscopic finding of polyposis throughout the gastrointestinal tract. It results from subepithelial aggregations of lymphoma cells (see answer fig 1
). MLP is
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Gut 2007 56: 905.[Extract] [Full Text] [PDF]
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