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Gut 2007;56:1046; doi:10.1136/gut.2006.101725
Copyright © 2007 BMJ Publishing Group Ltd & British Society of Gastroenterology.

EDITOR'S QUIZ: GI SNAPSHOT

Iron-deficiency anaemia

Deepak Joshi, Mohammed Rela, Paolo Rizzi, Michael Heneghan, John O’Grady, Bernard Portmann, John O’Donohue

Institute of Liver Studies, Kings College Hospital, London, UK

Correspondence to:
Correspondence to:
Dr J O’Donohue Department of Gastroenterology
King’s College Hospital, London SE5 9RS, UK; john.o’donohue@uhl.nhs.uk

The first 150 words of the full text of this article appear below.

Clinical presentation

A 62-year-old man with a history of chronic hepatitis B cirrhosis presented with deteriorating liver function. The serum {alpha} fetoprotein (AFP) level was 253 kU/l (normal upper limit <7 kU/l) and three lesions were found on CT of the liver; one of 4.5 cm diameter and two <1 cm. He underwent an orthotopic liver transplant, and hepatocellular carcinoma (HCC) was confirmed on histological examination of the explanted liver. The patient recovered uneventfully with good graft function.

At 2 months after surgery, the AFP level had increased to 1530 kU/l but no new lesions suggestive of HCC were demonstrated on CT of the liver and abdomen. The patient remained well with good graft function, but serial AFP measurements remained elevated (between 31 and 2476 kU/l). At 16 months after transplantation, the patient was noted to be persistently anaemic (serum haemoglobin 9.5 g/dl). Oesophagogastroduodenoscopy and colonoscopy were normal. Haemoglobin continued to fall to . . . [Full text of this article]


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EDITOR’S QUIZ: GI SNAPSHOT
Gut 2007 56: 1053. [Extract] [Full Text] [PDF]

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