EDITOR'S QUIZ: GI SNAPSHOT
EDITOR’S QUIZ: GI SNAPSHOT
| The first 150 words of the full text of this article appear below. |
From the question on page 1046
Figure 1 shows a 2x4 cm lesion situated 15 cm distal to the duodenal–jejunal flexure. The H&E-stained section (fig 2A) shows a poorly differentiated large cell neoplasm at the bottom of an ulcer. Immunochemical analysis (fig 2B) shows strong cytoplasmic positivity for hepatocyte-specific antigen (Hepar 1) characteristic of hepatocellular carcinoma (HCC). A diagnosis of HCC recurrence within the small bowel was made. The patient subsequently underwent small bowel resection of this lesion, and remains well 1 year after surgery.
Liver transplantation is a recognised treatment for HCC occurring in cirrhotic livers. Recent British Society of Gasteroenterology guidelines (2003) recommend orthotopic liver transplant (OLT) for patients with small tumours (<5 cm in the case of a single nodule, or up to three lesions 
3 cm), in whom there is a favourable outcome; however, tumour recurrence after OLT is common if lesions are >5
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Gut 2007 56: 1046.[Extract] [Full Text] [PDF]
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