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Gut 2008;57:15; doi:10.1136/gut.2006.112730
Copyright © 2008 BMJ Publishing Group Ltd & British Society of Gastroenterology.

Editor's quiz: GI snapshot

Fulminant Clostridium difficile colitis

J M Jansen, J F Bartelsman

Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Correspondence to:
Dr J M Jansen, Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; j.m.jansen@olvg.nl

The first 150 words of the full text of this article appear below.


CLINICAL PRESENTATION

A 39-year-old man with an unremarkable previous medical history was referred because of sepsis with multi-organ failure. He had undergone an ileocaecal resection in another hospital because of a peri-appendicular infiltrate complicated with an abdominal compartment syndrome. Because of diarrhoea, a sigmoidoscopy was performed, showing typical pseudomembranes as seen with Clostridium difficile infection. The patient was treated with vancomycine 125 mg four times daily and 1 g rectally combined with metronidazol 500 mg three times daily for 14 days. Less than a week after discontinuation of the antibiotics, he again developed diarrhoea and fever. At colonoscopy, once more a pseudomembranous colitis was seen. Vancomycin was started at a higher dose of 500 mg four times daily. His condition deteriorated and computer tomography (Gofigs 1 and 2) was performed.


 


 


QUESTION

What does the computer tomography scan of the abdomen show? See page 24 for . . . [Full text of this article]


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Gut 2008 57: 24. [Extract] [Full Text] [PDF]

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