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1 Department of Hepatology, University Hospital Gasthuisberg, University of Leuven, Belgium
2 Metabolic Center, Department of Paediatrics, University Hospital Gasthuisberg, University of Leuven, Belgium
Correspondence to:
Professor David Cassiman, Department of Hepatology and Metabolic Center, University Hospital Gasthuisberg, University of Leuven, Herestraat 49, 3000 Leuven, Belgium; David.cassiman@med.kuleuven.be
Revised version received 24 April 2007
Accepted 26 April 2007
| The first 150 words of the full text of this article appear below. |
The liver is a stupid organ. It has only limited abilities to express itself. It can necrotise, swell, inflame, clot and scarify. The liver can become leaky, it can sometimes hurt and its plumbing can clog. And then the liver can be fatty. For some time already, we know that, for example, several viruses can cause the inflammation, and that drugs, viruses and autoimmunity cause most of the necrosis, etc. Luckily, for the majority of these causes, we have more or less reliable methods to pin them down. Not so for the fatty sign because, when turning fatty, the liver is at its most stupid. On a communication scale and compared with the eloquent monologue of a viral hepatitis, turning fatty would rate as a grunt. It is never entirely clear what causes a grunt or what is meant by grunting, as it is never clear what provokes fatty infiltration
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