Digest
Digest
| The first 150 words of the full text of this article appear below. |
Although atrophic gastritis is a well recognised risk factor for non-cardia gastric cancer and gastro-oesophageal reflux disease (GORD) for oesophageal adenocarcinoma, the roles of atrophic gastritis and GORD in the aetiology of adenocarcinoma of the cardia is less clear. In this case–control study, Derakhshan et al evaluated risk factors for upper gastrointestinal adenocarcinoma. Non-cardia cancer was associated with atrophic gastritis but not with GORD symptoms, whereas the opposite was true for oesophageal adenocarcinoma. Cardia cancer was positively associated with both severe gastric atrophy and with frequent GORD symptoms, although the latter was only apparent in the non-atrophic subgroup and in the intestinal subtype. The association of cardia cancer with atrophy was stronger for the diffuse versus intestinal subtype and this was the converse of the association observed with non-cardia cancer. Based on their findings, the authors suggest there seem to be two distinct aetiologies of cardia cancer and propose that
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Relevant Articles
- Role of endogenous opioids in modulating HSC activity in vitro and liver fibrosis in vivo
- S De Minicis, C Candelaresi, M Marzioni, S Saccomano, T Roskams, A Casini, A Risaliti, R Salzano, N Cautero, F di Francesco, A Benedetti, and G Svegliati-Baroni
Gut 2008 57: 352-364.[Abstract] [Full Text] [PDF]
- Evidence for differential effects of hepcidin in macrophages and intestinal epithelial cells
- T Chaston, B Chung, M Mascarenhas, J Marks, B Patel, S K Srai, and P Sharp
Gut 2008 57: 374-382.[Abstract] [Full Text] [PDF]
- Brain-derived neurotrophic factor amplifies neurotransmitter responses and promotes synaptic communication in the enteric nervous system
- W Boesmans, P Gomes, J Janssens, J Tack, and P Vanden Berghe
Gut 2008 57: 314-322.[Abstract] [Full Text] [PDF]
- NOD2-expressing bone marrow-derived cells appear to regulate epithelial innate immunity of the transplanted human small intestine
- T Fishbein, G Novitskiy, L Mishra, C Matsumoto, S Kaufman, S Goyal, K Shetty, L Johnson, A Lu, A Wang, F Hu, B Kallakury, D Lough, and M Zasloff
Gut 2008 57: 323-330.[Abstract] [Full Text] [PDF]
- Severe paediatric ulcerative colitis: incidence, outcomes and optimal timing for second-line therapy
- D Turner, C M Walsh, E I Benchimol, E H Mann, K E Thomas, C Chow, R A McLernon, T D Walters, J Swales, A H Steinhart, and A M Griffiths
Gut 2008 57: 331-338.[Abstract] [Full Text] [PDF]
- Combination of gastric atrophy, reflux symptoms and histological subtype indicates two distinct aetiologies of gastric cardia cancer
- M H Derakhshan, R Malekzadeh, H Watabe, A Yazdanbod, V Fyfe, A Kazemi, N Rakhshani, R Didevar, M Sotoudeh, A A Zolfeghari, and K E L McColl
Gut 2008 57: 298-305.[Abstract] [Full Text] [PDF]
Services
- Email this link to a friend
- Similar articles in this journal
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
