Digest
Digest
| The first 150 words of the full text of this article appear below. |
Obesity is associated with increased risk for several cancers. Based on this, it has been speculated that this association might be due to factors secreted by adipose tissue. Leptin and adiponectin are adipokines that have been found to be associated with several malignancies but the relationship with Barrett’s oesophagus, the precursor of the majority of oesophageal adenocarcinomas, is unknown. In this Australian study, this relationship was investigated. There was a significant, three-fold increased risk of Barrett’s oesophagus among men in the highest quartile of serum leptin (see table) and this persisted after adjustment for reflux symptoms. On the contrary, a tendency towards decreased risk for Barrett’s oesophagus among women with increasing leptin levels was observed. No association with adiponectin was seen. Kendall et al conclude that there is an association between leptin and the presence of Barrett’s oesophagus in men—but not in women—and that this association is not explained
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Services
- Email this link to a friend
- Similar articles in this journal
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
