Digest
Digest
| The first 150 words of the full text of this article appear below. |
The increasing use of surveillance for preneoplastic and neoplastic lesions in Barrett’s oesophagus means that managing early lesions has become an important problem. Radical oesophagectomy has a high morbidity and mortality so endoscopic treatment is being increasingly advocated. The study by Pech and colleagues describing 349 patients who underwent endoscopic treatment for high-grade intraepithelial neoplasia and mucosal adenocarcinoma from 2002–6 is, therefore, of great interest. Endoscopic resection was performed in 279 patients with localised neoplasia, whilst 55 patients had photodynamic therapy. In the second half of the study period, the remaining non-neoplastic part of the Barrett’s epithelium was also ablated using argon plasma coagulation or photodynamic therapy. The overall complication rate was 17.2%, a quarter of which were oesophageal stenosis. A complete response was achieved in 96%; 3.7% of patients underwent surgery after failure of endoscopic therapy. Of the patients, 58 have died but none from Barrett’s neoplasia. As the
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Relevant Articles
- Long-term results and risk factor analysis for recurrence after curative endoscopic therapy in 349 patients with high-grade intraepithelial neoplasia and mucosal adenocarcinoma in Barrett’s oesophagus
- O Pech, A Behrens, A May, L Nachbar, L Gossner, T Rabenstein, H Manner, E Guenter, J Huijsmans, M Vieth, M Stolte, and C Ell
Gut 2008 57: 1200-1206.[Abstract] [Full Text] [PDF]
- Modelling future capacity needs and spending on colonoscopy in the English bowel cancer screening programme
- K E Nnoaham and C Lines
Gut 2008 57: 1238-1245.[Abstract] [Full Text] [PDF]
- Cost-effectiveness of and satisfaction with a Helicobacter pylori "test and treat" strategy compared with prompt endoscopy in young Asians with dyspepsia
- S Mahadeva, Y-C Chia, A Vinothini, M Mohazmi, and K-L Goh
Gut 2008 57: 1214-1220.[Abstract] [Full Text] [PDF]
- Comparing laparoscopic antireflux surgery with esomeprazole in the management of patients with chronic gastro-oesophageal reflux disease: a 3-year interim analysis of the LOTUS trial
- L Lundell, S Attwood, C Ell, R Fiocca, J-P Galmiche, J Hatlebakk, T Lind, O Junghard, and on behalf of the LOTUS trial collaborators
Gut 2008 57: 1207-1213.[Abstract] [Full Text] [PDF]
- Reliability of transient elastography for the diagnosis of advanced fibrosis in chronic hepatitis C
- U Arena, F Vizzutti, J G Abraldes, G Corti, C Stasi, S Moscarella, S Milani, E Lorefice, A Petrarca, R G Romanelli, G Laffi, J Bosch, F Marra, and M Pinzani
Gut 2008 57: 1288-1293.[Abstract] [Full Text] [PDF]
- Protease-activated receptor-2 activation: a major actor in intestinal inflammation
- E Hyun, P Andrade-Gordon, M Steinhoff, and N Vergnolle
Gut 2008 57: 1222-1229.[Abstract] [Full Text] [PDF]
Services
- Email this link to a friend
- Similar articles in this journal
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
