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Abstracts
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BSG inflammatory bowel disease symposium
A. R. Hart for The IBD in EPIC Study Investigators. School of Medicine, University of East Anglia, Norwich, UK
Introduction: Dietary docosahexaenoic acid (DHA), an n-3 polyunsaturated fatty acid obtained principally from fish, has anti-inflammatory effects on many cellular processes, and may prevent the development of ulcerative colitis. Currently, there are no prospective epidemiological data from multicentre studies investigating this hypothesis.
Aims and Methods: The aim was to examine the prospective relationship between the dietary intake of DHA and the development of ulcerative colitis in participants enrolled in a large European cohort study. The populations comprised 189 610 men and women, aged 30–74 years, participating in a cohort study (EPIC European Prospective Investigation Into Cancer & Nutrition). Participants were resident in either the UK, Sweden, Denmark or Germany. They provided information on diet at recruitment, by completing food frequency questionnaires, and were followed up for the diagnosis of ulcerative colitis.
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