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Permeability of the small intestine to substances of different molecular weight
  1. C. A. Loehry,
  2. A. T. R. Axon,
  3. P. J. Hilton,
  4. R. C. Hider,
  5. B. Creamer

    Abstract

    The permeability of the rabbit small intestine has been studied by measuring the plasma clearances of water-soluble molecules over the molecular weight range 60-33,000. An inverse relationship has been demonstrated between permeability and molecular weight.

    The significance of these findings in relation to current concepts of the `pore hypotheses' is discussed, and the possible physiological and pathological implications are considered.

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