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Effect of cigarette smoking on human gastric secretory responses
  1. H. T. Debas,
  2. M. M. Cohen,
  3. I. B. Holubitsky,
  4. R. C. Harrison

    Abstract

    The effect of smoking three cigarettes over a one-hour period on the pentagastrinstimulated submaximal plateau of acid and pepsin secretion was observed in 12 healthy human volunteers comprising men and women and smokers and non-smokers. No significant overall change in secretion was observed. In one subject, however, acid secretion was significantly inhibited (p < 0·01) and in one individual significant late stimulation (p < 0·01) of both acid and pepsin was observed.

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