The changes in osmotic pressure and the degree of marked dilution in the jejunal lumen after a hypertonic meal, have been studied in patients after truncal vagotomy and drainage, with and without diarrhoea, using an intraluminal intubation technique. The results suggest that neither the emptying of a hyperosmotic load from the stomach, nor its subsequent dilution in the jejunum have an important role in post-vagotomy diarrhoea.
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