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Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis.
  1. M Simon,
  2. M Bourel,
  3. R Fauchet,
  4. B Genetet

    Abstract

    The frequency of HLA-A3 and HLA-B14 antigens was significantly higher in a series of 51 patients with idiopathic haemochromatosis than in a control group, being respectively 78-4 versus 27-0% and 25-5 versus 3-4%. This finding strongly supports the suggestion that idiopathic haemochromatosis is a genetic disease and suggests that the gene(s) responsible for the disease may be linked to the histocompatibility genes.

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