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Double-blind trial of cholestyramine in post-vagotomy diarrhoea.
  1. V M Duncombe,
  2. T D Bolin,
  3. A E Davis

    Abstract

    The effect of cholestyramine in post-vagotomy diarrhoea has been assessed under double-blind conditions. Cholestyramine produced a significant improvement in frequency, urgency, and consistency of stool as well as episodic diarrhoea. Faecal bile acid excretion was significantly higher in the post-vagotomy group when compared with normal controls. These findings confirm the effectiveness of cholestyramine and support the concept of a bile acid mediated aetiology in post-vagotomy diarrhoea.

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