Article Text


Extramedullary haemopoiesis in the small bowel.
  1. B K Sharma,
  2. R E Pounder,
  3. J P Cruse,
  4. S M Knowles,
  5. A A Lewis


    A patient with myelofibrosis developed repeated gastrointestinal haemorrhage from the small intestine, which was found to be infiltrated with extramedullary haemopoiesis. Nineteen months later he presented with subacute intestinal obstruction; radiology and laparotomy documented progressive infiltration of the small bowel. Histological examination of the resected terminal ileum showed patchy mucosal ulceration, with underlying submucosal and serosal extramedullary haemopoiesis.

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