Article Text

PDF

Penetration of albendazole sulphoxide into hydatid cysts.
  1. D L Morris,
  2. J B Chinnery,
  3. G Georgiou,
  4. G Stamatakis,
  5. B Golematis

    Abstract

    The penetration of albendazole sulphoxide, the principal metabolite of albendazole into hydatid cysts (E granulosus) was measured by means of in vitro animal and clinical studies. The drug freely diffuses across the parasitic membranes. Cyst/serum concentrations of 22% were achieved in patients, longer pre-operative therapy produced higher concentrations.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.