Gut 29:548-549 doi:10.1136/gut.29.4.548
  • Research Article

Non-psychogenic primary polydipsia in autoimmune chronic active hepatitis with severe hyperglobulinaemia.

  1. M V Tobin,
  2. A I Morris
  1. Gastroenterology Unit, Royal Liverpool Hospital.


      The association of hyperglobulinaemia with renal tubular acidosis and nephrogenic diabetes insipidus is well established. A patient with marked hyperglobulinaemia due to autoimmune chronic active hepatitis is described who presented with severe polydipsia and polyuria but had entirely normal renal tubular function indicating a primary thirst disorder.