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IgA nephropathy in non-cirrhotic portal hypertension.
  1. C Babbs,
  2. T W Warnes,
  3. H B Torrance,
  4. F W Ballardie
  1. University Department of Gastroenterology Manchester Royal Infirmary.

    Abstract

    Renal glomerular changes are a well recognised complication of cirrhosis and are frequently characterised by mesangial IgA deposition. We report a patient with non-cirrhotic portal hypertension who developed IgA nephropathy and a nephrotic syndrome with renal histological changes classically associated with cirrhosis. Splenectomy with resection of a splenic artery aneurysm resulted in remission of the nephrotic syndrome. This case illustrates the factors which contribute to the pathogenesis of IgA nephropathy in liver disease.

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