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Recombinant interferon alfa-2b treatment in chronic non-A, non-B/type C hepatitis.
  1. V De Conca,
  2. S Mesiti,
  3. E Vallarino,
  4. A Mornese,
  5. M Dodero
  1. EO Ospedali Galliera, Genova, Italy.


    In a study of 60 patients with non-A, non-B/type C (NANB/C) chronic hepatitis alanine aminotransferase (ALT) activities returned to normal after treatment with interferon alfa-2b (3 million units for six months) in 70.7% and 29.3% did not respond. The response was maintained during four to six months, follow up in 41.4% of patients. Liver biopsy specimen showed histological improvement in all patients surveyed. Treatment was well tolerated with only mild side effects.

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