Article Text

PDF

Clinical and histological evaluation of interferon alfa-2b in the treatment of chronic hepatitis C.
  1. C Panella,
  2. A Francavilla,
  3. D Conte,
  4. I Tatulli,
  5. F Rubini
  1. Department of Gastroenterology, University of Bari, Italy.

    Abstract

    In a study of 37 patients with hepatitis C (proved histologically) positive chronic hepatitis, a correlation was seen between clinical efficacy and histological improvement after treatment with interferon alfa-2b (3 million units (MU) three times a week for six months plus six months' follow up). Alanine aminotransferase activities became normal in 18 (48%) patients during treatment; at the end of follow up eight (45%) had a continued response to the treatment. Paired liver biopsy specimens showed marked improvements in Knodell index score and portal inflammation in these patients.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.