Article Text

PDF

Quantitative hepatitis C virus RNA and liver histology in chronic hepatitis C patients treated with interferon alfa.
  1. G Yamada,
  2. M Takahashi,
  3. H Endo,
  4. T Doi,
  5. R Miyamoto,
  6. H Shimomura,
  7. K Yamamoto,
  8. T Tsuji
  1. First Department of Internal Medicine, Okayama University Medical School, Japan.

    Abstract

    Seventy patients with hepatitis C virus (HCV) infection received alpha interferon at doses ranging from 3 to 10 million units (MU) daily for eight weeks, three times weekly for 12-24 weeks, or daily and three times weekly for 12-24 weeks. The efficacy of interferon was closely related to the initial blood HCV-RNA values in that these were lower in those who responded completely and partially compared with non-responders. Continuous reductions in HCV-RNA and improvements in the histology activity index score were seen in those who responded completely. In contrast, most of the partial and non-responders remained HCV-RNA positive.

    Statistics from Altmetric.com

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.