Table 2
Characteristics of 10 patients with primary ileal villous atrophy (PIVA). Another patient reported in reference 6 had PIVA with collagenous colitis, but his characteristics were not described
| Variable | Cases from the literature | Present series | |||||||||
| Reference (patient) | |||||||||||
| 2 (KV) | 2 (NJ) | 2 (MM) | 1 | 3 | 4 | 5 | RM | DO | ML | ||
| Age at diagnosis (y)/sex | 66/F | 31/M | 36/M | 49/F | 63/F | 60/M | 75/M | 84/F | 55/F | 77/F | |
| Age at onset of diarrhoea (y) | 41 | 13 | 33 | 47 | ND | 45 | 74 | 34 | 34 | 61 | |
| Weight loss (kg) | 14 | 0 | 8 | 4 | 16 | 0 | 0 | No | No | 8 | |
| Faecal weight (g/24 h) | 370 | 439 | 411 | 600–2000 | 550–1850 | 490–610 | 450 | 940 | 300–1800 | 500–800 | |
| Faecal fat (g/24 h) (N<7) | 2 | 45 | 54 | 45 | ND | 3.2–3.9 | ND | 87 | ND | 2–5 | |
| Schilling test with intrinsic factor | N | N | N | Low | N | N | N | N | Low | N | |
| 75SeHCAT or cholylglycine test | Low | Low | Low | Low | Low | Low | N | N | N | Low | |
| Efficacy of cholestyramine | Yes | Yes | Yes | Partial | Yes | ND | Yes | No | Yes | ||
| Faecal weight during fasting test (g/24 h at days 2/3) | ND | ND | ND | ND | ND | ND | ND | 400/500 | 600/950 | 480/ND | |
| α1-antitrypsin clearance (ml/24 h)3-150 | ND | ND | ND | ND | ND | ND | ND | 59 | 62 | 5–40 | |
| Colon histology | N | N | N | Excess of plasma cells in rectum | LC | N | LC | LC | LC | LC | |
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↵3-150 Normal <10 ml/24 h. ND, not described.
