Effect of the various diets and combinations on faecal pH and on parameters of microcirculation
| Diet | Faecal pH | Adherence (per 100 μm venule) | Emigration (per microscopic field) | Leucocyte rolling velocity (μm/s) | Shear rate (s−1) | Macroscopic score (arbitrary units) |
| FP/FR | 7.76 (0.14) | 5.95 (0.53)3-150 | 4.15 (0.53) | 61.2 (3.3) | 415 (19) | 3.9 (0.6) |
| US/FR | 7.85 (0.09) | 4.48 (0.44) | 1.13 (0.19)3-150 | 75.8 (3.2) | 420 (18) | 2.5 (0.7) |
| ST/CR | 7.98 (0.24) | 3.59 (0.42)3-150 | 1.49 (0.19)3-150 | 70.7 (3.7) | 409 (18) | 3.8 (0.3) |
| ST/ST | 7.99 (0.05) | 4.71 (0.36) | 4.57 (0.43) | 69.8 (2.4) | 429 (11) | 3.5 (0.4) |
| US/US | 8.00 (0.17) | 4.40 (0.44) | 2.19 (0.28)3-150 | 69.4 (3.4) | 391 (17) | 2.8 (0.8) |
| CP/FR | 8.01 (0.19) | 3.48 (0.31)3-150 | 3.36 (0.33)3-150 | 73.8 (4.0) | 400 (13) | 3.7 (0.9) |
| FP/FP | 8.11 (0.09) | 4.29 (0.38) | 2.93 (0.47)3-150 | 59.1 (3.4) | 403 (17) | 2.3 (0.2)3-150 |
| FP/ST | 8.14 (0.25) | 3.92 (0.38) | 4.97 (0.81) | 68.5 (5.3) | 440 (21) | 2.9 (0.5) |
| CR/ST | 8.16 (0.16) | 3.67 (0.48)3-150 | 1.55 (0.32)3-150 | 59.3 (3.5) | 434 (25) | 2.0 (1.0)3-150 |
| US/ST | 8.24 (0.35) | 3.15 (0.32)3-150 | 1.65 (0.28)3-150 | 73.3 (3.5) | 452 (19) | 3.0 (0.3) |
| ST/US | 8.25 (0.9)3-150 | 3.54 (0.44)3-150 | 3.51 (0.45)3-150 | 68.1 (3.0) | 470 (19) | 2.3 (0.7) |
| SA/SA | 8.33 (0.03)3-150 | 2.29 (0.23)3-150 | 1.56 (0.22)3-150 | 81.5 (2.8) | 500 (19)3-150 | 1.1 (0.5)3-150 |
| ST/SA | 8.34 (0.02)3-150 | 3.56 (0.40)3-150 | 3.32 (0.47)3-150 | 69.1 (2.8) | 411 (14) | 2.4 (0.7) |
| C1 | 8.34 (0.12)3-150 | 2.33 (0.27)3-150 | 2.00 (0.23)3-150 | 70.6 (2.7) | 493 (24)3-150 | 0.8 (0.1)3-150 |
| C2 | 8.39 (0.03)3-150 | 3.37 (0.54)3-150 | 0.68 (0.20)3-150 | 72.8 (4.5) | 487 (26)3-150 | 2.3 (0.5)3-150 |
| SA/FR | 8.42 (0.21)3-150 | 2.52 (0.22)3-150 | 1.86 (0.27)3-150 | 53.6 (2.8) | 564 (17)3-150 | 0.3 (0.2)3-150 |
| CP/ST | 8.43 (0.19)3-150 | 3.53 (0.46)3-150 | 2.12 (0.34)3-150 | 71.7 (3.3) | 445 (23) | 1.8 (0.6)3-150 |
| ST/CH | 8.46 (0.16)3-150 | 3.56 (0.26)3-150 | 3.03 (0.24)3-150 | 75.6 (2.5) | 429 (11) | 0.7 (0.2)3-150 |
| ST/FR | 8.50 (0.07)3-150 | 3.48 (0.27)3-150 | 3.95 (0.40) | 82.2 (2.3) | 439 (11) | 1.5 (0.5)3-150 |
| CR/CR | 8.52 (0.14)3-150 | 1.80 (0.25)3-150 | 1.06 (0.32)3-150 | 65.9 (2.8) | 475 (15) | 0.6 (0.1)3-150 |
| Control | 8.54 (0.06)3-150 | 2.07 (0.23)3-150 | 1.43 (0.19)3-150 | 77.0 (2.5) | 526 (17)3-150 | 0.6 (0.2)3-150 |
| PS1 | 8.56 (0.05)3-150 | 2.13 (0.21)3-150 | 0.54 (0.10)3-150 | 64.6 (3.3) | 495 (24)3-150 | 0.3 (0.2)3-150 |
| HC2 | 8.61 (0.18)3-150 | 3.10 (0.41)3-150 | 1.62 (0.27)3-150 | 61.9 (3.2) | 485 (20)3-150 | 1.1 (0.3)3-150 |
| PS2 | 8.64 (0.03)3-150 | 1.60 (0.20)3-150 | 1.60 (0.17)3-150 | 65.4 (3.0) | 440 (19) | 1.3 (0.8)3-150 |
| CP/CP | 8.83 (0.14)3-150 | 2.12 (0.21)3-150 | 1.89 (0.37)3-150 | 62.5 (3.0) | 435 (17) | 0.8 (0.3)3-150 |
| HC1 | 8.83 (0.15)3-150 | 1.82 (0.22)3-150 | 0.92 (0.18)3-150 | 72.8 (2.7) | 537 (27)3-150 | 0.3 (0.1)3-150 |
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Data are expressed as mean (SEM).
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↵3-150 p < 0.05 v ST/ST.
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ST, standard diet; CH, diet rich in carbohydrates; FR, diet rich in fatty acids; FP, diet poor in fatty acids; CR, diet rich in cholesterol; CP, diet poor in cholesterol; SA, diet poor in saturated fatty acids; US, diet poor in unsaturated fatty acids. All diet combinations (except the control) contain indomethacin. HC, potassium hydrogen citrate; PS, polysulphonic acid; C, cholestyramine; 1, without indomethacin; 2, with indomethacin (all alkalising drugs combined with standard diet).
