Table 2
CTLA-4 genotypes in HLA class II matched patients with coeliac disease and controls
| HLA genotype | |||
|---|---|---|---|
| AA | AG | GG | |
| HLA DR3 positive3-150 | |||
| Coeliac disease | 46 (65.7) | 21 (30.0) | 3 (4.3) |
| Controls | 8 (33.4) | 11 (45.8) | 5 (20.8) |
| HLA DR3 negative† | |||
| Coeliac disease | 23 (74.2) | 7 (22.6) | 1 (3.2) |
| Controls | 54 (51.0) | 36 (34.0) | 16 (15.0) |
| HLA DQB13-15002 positive‡ | |||
| Coeliac disease | 64 (68.0) | 26 (27.7) | 4 (4.3) |
| Controls | 19 (43.2) | 17 (38.6) | 8 (18.2) |
| HLA DQA13-1500501/DQB13-15002 positive§ | |||
| Coeliac disease | 59 (70.2) | 21 (25.0) | 4 (4.8) |
| Controls | 9 (34.6) | 12 (46.2) | 5 (19.2) |
-
Results are expressed as number (%).
-
χ2 test of heterogeneity (2 DF) using a 3×2 contingency table.
-
↵3-150 p=0.005; †p=0.04; ‡p=0.004; §p=0.002.
