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Gut 43:499-505 doi:10.1136/gut.43.4.499
  • Inflammation and inflammatory bowel disease

Increased state of activation of CD4 positive T cells and elevated interferon γ production in pouchitis

Table 3

Morphometric data for inflamed and non-inflamed pouch and ileal mucosa

UC with pouchitis UC without pouchitis FAP without pouchitis
Pouch (n=8) Ileum (n=5) Pouch (n=10) Ileum (n=7) Pouch (n=9) Ileum (n=3)
Villous length (μm) 376 (21–637) 595 (527–720) 393 (293–511) 533 (304–659) 406 (334–463) 490 (332–569)
Crypt depth (μm) 352 (291–492) 181 (129–418) 239 (141–422) 171 (136–215) 270 (241–417) 196 (159–238)
Villous surface area (mm2) 0.31 (0.1–0.62) 0.41 (0.37–0.74) 0.26 (0.19–0.30) 0.28 (0.14–0.42) 0.21 (0.17–0.38) 0.32 (0.27–0.41)

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