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Gut 45:389-394 doi:10.1136/gut.45.3.389
  • Inflammation and inflammatory bowel disease

Increased prevalence of methylenetetrahydrofolate reductase C677T variant in patients with inflammatory bowel disease, and its clinical implications

Table 9

Effect of folic acid treatment (400 μg/day) for six weeks in patients with inflammatory bowel disease (IBD) (n=39)

Pretreatment Post-treatment p Value
tHcy 13.6 (5.40–37.95)   9.01 (4.96–17.16) 0.0001
PF 4.15 (1.85–13.50) 25.10 (4.10–150) 0.0001
RCF 381 (113–1063) 703 (184–2070) 0.0001
Vitamin B12  365 (219–694) 393 (188–716) 0.70
  • tHcy, homocysteine; PF, plasma folate; RCF, red cell folate.

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