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Gut 46:40-45 doi:10.1136/gut.46.1.40
  • Small intestine

Diversion of intestinal flow decreases the numbers of interleukin 4 secreting and interferon γ secreting T lymphocytes in small bowel mucosa

Table 2

Lymphocyte activation markers in non-diverted and diverted intestinal mucosa

IELs LPLs
Non-diverted Diverted Non-diverted Diverted
Colon cancer 1
 CD25 0.5 0.2 1.6 2.2
 CD69 99.5 98.9 97 93.4
Colon cancer 2
 CD25 2.0 0 2.6 1.6
 CD69 98.5 99.5 90.2 91.2
Ulcerative colitis
 CD25 1.3 0 0.7 0.4
 CD69 99.2 99.3 98.4 97.8
Crohn's disease
 CD25 1.3 0.4 ND ND
 CD69 90.3 96.4 ND ND
  • Results expressed as percentage of CD3 lymphocytes expressing the activation marker.

  • IEL, intraepithelial lymphocyte; LPL, lamina propria lymphocyte; ND, not determined.

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