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Gut 46:500-506 doi:10.1136/gut.46.4.500
  • Inflammation and inflammatory bowel disease

A decision analysis of surveillance for colorectal cancer in ulcerative colitis

Table 1

Baseline assumptions and range tested in the sensitivity analysis

Baseline model Sensitivity analysis
Sensitivity in detecting dysplasia and CRC 90% 50–100%
Specificity of surveillance in detecting dysplasia and CRC 95% 80–100%
Case fatality rate of CRC in surveillance 13% 5–45%
Health related quality of life after proctocolectomy 95% 85–100%
Surveillance interval 2 y 1–5 y
Time lag between dysplasia and CRC 3 y 1–5 y
Costs per surveillance colonoscopy $911 $200–$1500
Costs of proctocolectomy $8300 $4150–$16 600
Costs of terminal care per patient with CRC $34 100 $17 050–$68 200
Average annual income $24 294 $10 000–$50 000
Annual discount rate 3%
  • CRC, colorectal cancer.

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